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In clinical trials, near-ultraviolet light (NUV) has been used for nerve visualization in surgery and shown beneficial effects within the surgical field [174]

Notably, excessive ROS can further exacerbate calcium homeostasis disorders by damaging the sarcoplasmic reticulum Ca-ATPase and mitochondrial calcium uniporter, forming a malignant cascade of excessive ROS-calcium imbalance-energy crisis [136]

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