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An early multicenter, randomized, placebo-controlled study in individuals with AD of moderate severity found that supplementation with 2,000 IU/day of all - rac --tocopherol (equivalent to 900 mg/day of RRR --tocopherol) for two years significantly delayed cognitive decline, slowed disease progression, and increased median survival (107)

With a genetic disease like autism, theres the concept of a double hit. You might have a gene mutation that gets you close to the threshold for autism, and then you experience another insult (medical event or environmental exposure) that confounds it and pushes you over the line

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