Long-term supplementation has been associated with slightly reduced zinc levels, necessitating monitoring in individuals taking glutathione for extended periods
Notably, AcM concentration also led to a decreased ability of the caecal microbiota to generate energy through functions such as glycolysis and to a reduction in the metabolism of ribosomal protein and nucleotides, together with a depletion of DNA homologous recombination, replication, and mismatch repair
Bottom line: Using a liposomal format can significantly reduce the likelihood of stomach upset because the glutathione is protected and absorbed more efficiently, rather than sitting in the gut and causing irritation
For this experiment, the aim is to do concave maximisation, which is simply to search for the optimum Vmax, that can be assumed relevant to the in vitro enzyme level, for the maximum glutathione production