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Beneficial effects of alpha-lipoic acid and ascorbic acid on endothelium-dependent, nitric oxide-mediated vasodilation in diabetic patients: relation to parameters of oxidative stress

Ingredients: Isododecane, Hydrogenated Polyisobutene, Dimethicone, Dimethiconol, Isopropyl Myristate, Fragrance, C13-16 Isoparaffin, Polysilicone-13, C10-13 Isoparaffin, Squalane, Tocopherol, Di(Phytosteryl/Octyldodecyl) Lauroyl Glutamate, Water, Bg, Sericin, Potassium Sorbate, Citric Acid, Hydrolyzed Conchiolin Protein, Amodimethicone, Ppg-2-Deceth-12, Glycerin, Phenoxyethanol, Lactic Acid

This phenomenon, sometimes called tolerance or dose creep, is reported anecdotally with tirzepatide, though the clinical trial data does not show significant tolerance development at fixed doses over 72 weeks

It stimulates new collagen elastin and has been shown to improve overall texture of the skin, like the size of your pores