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If your headaches persist or worsen, contact your healthcare professional

N Engl J Med 2021;384:989-1002.ArticlePubMed 33

The authors of the review acknowledge the various limitations of their research

However, the administered NA dose was based on efficiency in hypercholesterolemia studies, therefore, an optimal NA dose for mitochondrial myopathy has to be determined, especially considering that another study found an association between metabolites of excess NA, 2PY, and 4PY, and cardiovascular disease (CVD) 245