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Experimental autoimmune thyroiditis (EAT) models have demonstrated that pharmacological blockade of S1P signaling ameliorates thyroid inflammation and reduces TSH levels, underscoring a bidirectional crosstalk between thyroid dysfunction and liver inflammation via ECM pathways (93)

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Gut Microbes 3(1):414

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Emodin is an emodin compound isolated from Rheum palmatum L

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