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Unfortunately, they do not reduce the risk of cardiovascular disease or prevent loss of renal function

Inhibition of these two enzymes can be a useful strategy for controlling blood sugar levels in people with diabetes

Ferroptosis describes a form of regulated cell death that is driven by unrestricted lipid peroxidation, which does not require the activation of caspase and can be suppressed by iron chelators, lipophilic antioxidants, inhibitors of lipid peroxidation, and depletion of polyunsaturated fatty acids (PUFAs) [6, 7]

Early data suggest that these interventions are generally safe, but concurrent use with existing treatment paradigms requires further evaluation in a controlled setting to avoid unanticipated adverse effects or efficacy reduction