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[68] And some articles in the popular press, such as those criticizing the pharmaceutical industry for marketing drugs for off-label use (with concern of ethics violations) have made strong statements about whether doctors can prescribe HGH off-label: "Unlike other prescription drugs, HGH may be prescribed only for specific uses

Many people begin to notice a brighter, more "rested" look in their skin within 4 to 8 weeks of consistent use, while more significant changes in skin tone may take 3 to 6 months

Higher doses would likely increase side effects without proportional benefits

Increasing water intake to produce at least 2.5 liters of urine daily, reducing salt intake, and balancing calcium and oxalate in the diet are key strategies