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Until just a few years ago, doctors really didnt have anything that worked, says Clyde Yancy, chief of cardiology at the Northwestern University Feinberg School of Medicine in Chicago

The four-week intervals Each dose is held for four weeks before the next increase

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FDA's evaluation concluded that the criteria weighed against placement on the list, citing inadequate physicochemical characterization, immunogenicity concerns from impurities and aggregates, lack of clinical effectiveness data for any approved use, and absence of published human exposure data for the proposed subcutaneous and topical routes