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The new findings suggest another possible application for those compounds, while their existing development provides proof of concept that the enzyme can be targeted with drugs

The indications for CE included obscure gastrointestinal bleeding (total n = 21, PEG only = 11, PEG with coffe enema = 10) and anemia (total n = 4, PEG only = 1, PEG with coffee enema = 3), whereas the other nine subjects were volunteers (PEG only = 5, PEG with coffee enema = 4)