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Data availability All original data can be accessed in the The FDA Adverse Event Reporting System (FAERS) database ( References Khan, M

Liver tissue samples were homogenized in a lysis buffer containing 50 mM Tris/HCl (pH 7.4), 150 mM sodium chloride, 1 mM EDTA, 5 mM sodium pyrophosphate, 1 mM sodium orthovanadate, 50 mM sodium fluoride, 1% NP-40, 1 mM PMSF and a protease inhibitor cocktail tablet (Roche Diagnostics Ltd.)

Enhancing stem cell function via culturing under hypoxic condition, which is known to prime MSCs to reduce cellular ROS levels, improved chondrogenic differentiation of MSCs [20] and cartilage regeneration in both post-traumatic and focal early OA rabbit models [21]

By contrast, fewer studies have investigated the impact and translational potential of targeting AR in other cancer types where it is also expressed and functional