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TB500 is only available as a injection

Both are dominated by gastrointestinal adverse events nausea, constipation, diarrhea, vomiting that are mostly mild-to-moderate and dose-related

Among studies of semen quality parameters, a systematic review of the human epidemiological data concluded that there was moderate to robust evidence for reductions in semen quality in relation to phthalate exposure levels on the basis of consistent findings across up to 14 different studies (83)

The 6 patients receiving TB4 experienced a 35.1% decrease in eye discomfort and a 59.1% reduction in total corneal fluorescein staining, relative to the control group [35]