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Although not all-inclusive, here are some of the signs: Loss of interest in previously valued activities and relationships Increased frequency and/or amount of drug use to achieve the same effect An inability to experience the same high that occurred with initial use The prioritization of drug use over activities and relationship Ongoing use despite negative consequences as a result of use Physical and psychological withdrawal without use The process of addiction, the time it takes to become addicted, and the impact of drugs on the brain can occur with one use or with repeated use

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