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There was high certainty that quit rates were higher in people randomized to nicotine e-cigarettes than in those randomized to nicotine replacement therapy (risk ratio [RR]1.63, 95% confidence interval [CI] 1.30 to 2.04) and moderate-certainty evidence, limited by imprecision, that quit rates were higher in people randomized to nicotine e-cigarettes than to e-cigarettes without nicotine (RR 1.94, 95% CI 1.21 to 3.13)

This cigarette is perfect for smokers who look for a gentler touch but still crave the distinct, natural qualities that define American Spirit

It is not completely hands-off, though

A resident of Kudus named Nitisemito had the idea of starting serial production and selling kreteks under a proprietary brand name