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Physical dependence Nicotine is the active component in tobacco responsible for physical dependence

This approach is crucial for individuals grappling with addiction as it enhances the potential for successful recovery while diminishing relapse risks

Dixon BN, Ugwoaba UA, Brockmann AN, et al

Toxicol Mech Methods 26:443454 Luedicke F, Picavet P, Baker G, Haziza C, Poux V, Lama N, Weitkunat R (2018) Effects of switching to the menthol tobacco heating system 2.2, smoking abstinence or continuing cigarettes on biomarkers of exposure: a randomized controlled, open-label, multicentre study in sequential confinement and ambulatory settings (Part 1)