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According to Ivan Berlin, toxicologist in Paris and Lausanne and an internationally renowned expert in this area, a single higher dose of nicotine increases addiction: When we talk of greater dependence, were talking about the difficulty of saying no, and thus greater toxicity, Jacques Cornuz, director of the outpatient clinic at the University of Lausanne, who is an epidemiologist and tobacco specialist who led the Federal Commission for the Prevention of Smoking (CFPT) from 2007 to 2014