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In tumors, actin is known to play important roles, including roles in gene expression and transcription, metastatic migration, survival in the bloodstream by protecting the tumor cells from being degraded and aiding in attachment to platelets, and extravasation (158), and intracellular pathogens are known to be able to hijack polymerization of actin and hijack actin-associated proteins in order to rearrange actin structures for their benefit (159)

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