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Future research to identify other susceptibility factors, such as genes that modify carcinogen metabolism or DNA repair, will need to be substantially larger and to quantify lifetime tobacco exposure with more precision than have past studies in order to distinguish gradations in risk due to exposure from those caused by genetic susceptibility

Tobacco and nicotine products are regulated and harmful to health

Smoking has a significant impact on your body

'Simple takeaway' The simple takeaway is the more you smoke, the more you stroke, said lead study author Janina Markidan of the University of Maryland School of Medicine in Baltimore