Other factors include, but are not limited to: 1 Age nicotine clearance decreases with age Sex studies have found women metabolize nicotine and cotinine faster than men Estrogen hormones there is a strong relationship between high estrogen levels, observed in premenopausal women, and increased metabolism of nicotine Smoking tobacco itself can also impact how long nicotine stays in your system
Secondhand smoke exposure causes heart disease, stroke, and lung cancer among adults, as well as respiratory disease, ear infections, sudden infant death syndrome, more severe and frequent asthma attacks, and slowed lung growth in children
"Passive Smoking and Heart Disease: Mechanisms and Risk"
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