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For azithromycin, he says caution is needed for people who have had a previous allergic reaction to other macrolide antibiotics, such as clarithromycin or erythromycin, and for those who are taking certain cholesterol medications, such as lovastatin or simvastatin, or medications that modify the heartbeat, such as, but not limited to, amiodarone, flecainide, mexiletine, sotalol, and dofetilide