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For the 7-mg and 10-mg ISO tar yield ECs, however, few compounds were significantly reduced, showing that the effect of split-tipping was diminished at low ventilation levels

In the present study, downregulation of FoxA2 expression was accompanied by downregulation of E-cadherin expression in airway epithelial cells and in lung tissue of animals exposed to CS, further indicating that smoking results in abnormal differentiation of airway epithelial cells

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