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Why it happens: Nicotine is a stimulant and can naturally raise heart rate, especially in people who are sensitive to it or are using a higher dose than needed

Cigarette smoking is a well-documented risk factor for various cardiovascular diseases, including atherosclerotic coronary artery disease, peripheral vascular disease, cerebrovascular disease, and abdominal aortic aneurysm, affecting blood vessels of different sizes 15,32

At the same time, cigarette smoke impairs innate defense mechanisms by macrophages, epithelial cells, dendritic cells, and natural killer cells, thereby increasing the risk, severity, and duration of infection

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