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This study aims for a broader grasp of the process of becoming not only smoke-free but also snus-free, i.e., from initiation as an aid to giving up smoking to final cessation of snus as well

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1 Introduction High-titer antinuclear antibodies (ANA) are biomarkers associated with many autoimmune diseases ( Smoking tobacco is a major cause of preventable deaths, illnesses, and health care costs worldwide ( In this article, we explore whether the decrease in cigarette smoking over the past few decades ( The effects of smoking and CO on autoimmune diseases depend on individual variability, exposure levels, and the disease in question