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Discussion Our present study aims to test two hypotheses: (1) whether the use of e-cigarettes at baseline can be helpful in combustible cigarette smoking cessation, and (2) how the use of e-cigarettes at baseline affects combustible cigarette consumption at follow-up among adolescent smokers

Table 2 a Patient-Reported Outcomes Measurement Information System Global Physical Health (GPH) and Global Mental Health (GMH) scales

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As a result, nicotine may stimulate and ultimately affect short-term brain functions such as emotion, learning, and memory