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This makes the body more vulnerable to infections

Radiographics 33:19511976 Elicker BM, Jones KD, Henry TS, Collard HR (2016) Multidisciplinary approach to hypersensitivity pneumonitis

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Each time you get a cold sore, the outbreak should follow the same five stages: An itching, tingling or burning sensation starts on and around your lip (known as the prodromal stage) One blister or a tight cluster of blisters form A few days later, the blisters burst and drain fluid (this is when they are most contagious) The blisters scab over The scab heals and falls off, leaving clear skin behind This progression occurs over the course of 7-10 days