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The comparison only looks concerning when you pit the whole device against a single cigarette, which is not a fair equivalency

The western blot results further supported that ENDS increased the expression level of CD71 and ACSL4, confirming ENDS could induce ferroptosis in bronchial epithelial cells ( Figure 6E )

Cancer Risk Starts Rising Sharply Smoking for 5 years increases: Lung cancer risk by 3040% Throat cancer risk significantly Risk of chronic inflammation and pre-cancerous lesions Breathing Capacity Drops Many smokers experience: Shortness of breath on exertion Wheezing Reduced stamina persistent phlegm HRCT scans often demonstrate early emphysema, airway obstruction, and bronchiolar thickening

“We cannot assume they are safe until we know more about possible risks, including cancer and COPD