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The analysis, which reviewed the available research and used a mathematical model for its projections, concluded that increasing the minimum legal age to 21 would decrease smoking initiation rates by 25 percent among 15- to 17-year-olds, while other age groups up to 21 years old would see smaller but significant decreases

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"Just as with the 'hard' drugs of abuse, such as heroin and cocaine, the phenomena of pleasure, addiction, increased tolerance and craving from tobacco are firmly rooted in neurochemistry." The research will be presented Tuesday in San Diego at the annual meeting of the Society for Neuroscience.