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Since the activity of CYP1A2 varies greatly from individual to individual, literature evidenced that there are different influential factors, such as genetics, coffee consumption, oral contraceptive use and smoking, even if the mechanisms are complex and not completely clear [21]

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Its unique lid design with built-in filter draws in smoke before it can be released into the air

This could be because of behavioural differences in younger children, such as placing hands and other objects in the mouth more often, or in how younger children tend to absorb more lead than adolescents and adults