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5557 Hoffmann et al 16 suggested that cigarette smoke induced morphologic changes in the COPD epithelium by significantly increasing the expression of Mfn1/2 and Opa1, which were accompanied by increased levels of the proinflammatory mediators such as IL-8, IL-6 and IL-1

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This is the first technology that could save millions of lives from tobacco-related illness and death. Although not sold as a device to help quit smoking, electronic cigarettes have shown a 50- to 70-percent success rate for smokers who wanted to quit (compared to a 3 percent success rate for the nicotine patch, a 4 percent success rate for gum and a 6 percent success rate for pharmaceuticals, Cameron said)

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