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The sample size of smokers in the study is nationally representative of the Centers for Disease Controls estimate that nearly 18% of American adults identify themselves as smokers

Nicotine is an appetite suppressant, reducing feelings of hunger

RAND Corporation researchers Morral, McCaffrey, and Paddock (2002) demonstrated mathematically that the gateway sequence could be fully explained by individual drug propensity and opportunity alone, without requiring any neurobiological priming mechanism to produce the observed epidemiological patterns

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