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Eng Es It Sp Learn about the health effects of e-cigarettes E-cigarettes are sometimes called e-cigs, vapes, e-hookahs, vape pens, and electronic smoking devices (ESDs). E-cigarettes produce an aerosol (vapor) by heating a liquid that usually contains nicotine, the addictive drug in regular cigarettes, cigars, and other tobacco products, flavorings, and other chemicals